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· The one topic that appears to have been replicated numerous times is the effects on erectile dysfunction, with the caveat that all of the studies are confounded with the inclusion of l-arginine. So the effects of Pycnogenol alone on erectile dysfunction are still unknown.
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While the rationale behind why it would work is airtight, the research on arginine’s actual effect on erectile dysfunction is. minimal side effects, and potential benefit on heart disease.
· L-arginine: Some evidence shows that taking high doses improves erectile dysfunction by stimulating blood vessels to open wider for improved blood flow. Side effects may include nausea, cramps and diarrhea. Don’t take L-arginine with sildenafil (Viagra). Ginseng
It appears to be a promising addition to first-line therapy for ED.. Lizza, E. Effect of large doses of the nitric oxide precursor, L-arginine, on erectile dysfunction.
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· The study further concludes that apart from the oral administration of L-arginine and Pycnogenol being effective in treating erectile dysfunction, the compounds also do not have any side effects. These studies exploring the use of pycnogenol and l-arginine for erectile dysfunction, gave dosages of 1.7 grams of L-Arginine daily along with 2 – 40.
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